Fluoride Interactions

Interactions with Medications and Supplements

The following are the medications and supplements that are more likely to cause a reaction with fluoride supplements:

  • Aluminium hydroxide
    Aluminium hydroxide (an antacid) decreases absorption of fluoride, so this medication should be taken at least 2 hours before or after taking fluoride supplements.
  • Calcium supplements
    Calcium supplements decrease absorption of fluoride, so should be taken several hours apart or not at all.
  • Milk and other dairy products
    Milk, just like calcium supplements causes fluoride to be less absorbed, so take fluoride supplements at least 2 hours before or after drinking milk (or larger amounts of other dairy products such as cheese, yoghurt or cream).
  • Vitamin C and glutathione
    Vitamin C and glutathione both detoxify the body of excess levels of fluoride, by reducing absorption of fluoride.
Calcium supplements decrease absorption of fluoride, so should be taken several hours apart or not at all

Other interactions with Fluoride

There are none reported.

Fluoride's effect on lab tests

Fluoride has the following effects on lab tests:

  • Serum calcium
  • Serum phosphatase
  • Protein-bound iodine
  • Serum aspartate aminotransferase (SGOT)

Fluoride supplements can cause falsely decreased levels of serum calcium, phosphatase and protein-bound iodine as well as falsely increased levels of SGOT.

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